Scientist I - Computational Genomics

Philadelphia, PA, US, 19104

​Location: LOC_COLKET-Colket Translational Research 

Req ID: 223214

Shift: Days

Employment Status: Regular - Full Time 


Seeking Breakthrough Makers   

Children’s Hospital of Philadelphia (CHOP)—named America’s 2022 Best Large Employer by Forbes—offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation.

At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care—and your career. 


CHOP’s Commitment to Diversity, Equity, and Inclusion 

CHOP is committed to building an inclusive culture where employees feel a sense of belonging, connection, and community within their workplace. We are a team dedicated to fostering an environment that allows for all to be their authentic selves. We are focused on attracting, cultivating, and retaining diverse talent who can help us deliver on our mission to be a world leader in the advancement of healthcare for children. 

We strongly encourage all candidates of diverse backgrounds and lived experiences to apply. 

Job Summary

Principal contributions are scientific or intellectual, characterized by originality and creativity. Works under the mentorship of an established principal investigator to conduct research in a specific scientific area. Initiates and conducts independent experiments without direct supervision. Develops own research project with the guidance of the principal investigator. Develops new experimental procedures and hypotheses for further investigation. Prepares manuscripts and abstracts for publication. Publishes scientific articles in refereed journals. Collaborates and interacts with other researchers within the institution and at other institutions. Assists in the preparation of scientific publications and research grant proposals. Serves as resource person for colleagues and as a mentor for less experienced research personnel. May manages/supervises other research staff or projects; assists with the management of laboratory operations.


Primary Job Responsibilities

  1. Lead long-reads methods development and data analysis projects, to implement and improve deep learning toolbox to extract biological information from signals of various long-read platforms.
  2. Interpret scientific results and submit findings in peer-review journals and present at national or international meetings, prepare and organize preliminary data for grant applications
  3. Mentor and collaborate with junior members of the research laboratory on scientific development and manuscript preparation

Job Responsibilities (Continued)

  • Conducts research of significant scientific value in the basic and/or translational science area(s) relevant to their practice specialty.
  • Participates in the design, planning and conduct of one or more experiments.
  • Trains technical staff, students, fellows & physicians in lab procedures.
  • Monitors daily resource allocations and day-to-day lab personnel activities.
  • Composes/Assists in developing publications for peer reviewed, scientific, quality and management, Journals.
  • Assists with the submission of applications for grants/contracts for funding of research projects.
  • Collaborates with researchers, external agencies and institutions to develop cooperative research initiatives.
  • Responsible for appropriate use of research funds.
  • May supervise technical staff and students.
  • May participate in educational programs and teaching assignments.

Required Education and Experience

Required Education: Master's Degree


Preferred Education: 

  • Doctorate with two (2) years or more of Post-Doctoral fellowship or scientifically relevant experience 
  • Master's Degree with six (6) or more years of scientifically relevant experience

Preferred Education, Experience & Cert/Lic

• PhD in Computer Science, Statistics, Bioinformatics, Genetics, Genomics, Biomedical Engineering or a related discipline.  

• Good understanding of deep learning algorithms, strong programming skills, and experience in one or more of the following areas: genomics algorithms development, transcriptome analysis, machine learning.  

• Strong and genuine interests in human genetics and common complex disease. 

• Two years of working experience with genomic/genetic data analyses are desirable. 

Additional Technical Requirements

  • 100% of effort is funded by Principal Investigator(s) grants

  • Scientific/intellectual contributions characterized by the unique & autonomous creativity

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community.  As a condition of employment, professionals working onsite—at any CHOP location, for any portion of time—must be vaccinated for COVID-19. Learn more. 

CHOP also requires employees who work in patient care buildings to receive an annual influenza vaccine. Employees may request exemptions for valid religious and medical reasons.  Start dates may be delayed until candidates are immunized or exemption requests are reviewed.  

EEO / VEVRAA Federal Contractor        |              Tobacco Statement 


Nearest Major Market: Philadelphia

Job Segment: Patient Care, Pathology, Pediatric, Computer Science, Data Analyst, Healthcare, Data, Technology