Research Tech IV-Human Molecular Genetics

Philadelphia, PA, US, 19104

Job Type: 

COLKET - Colket Translational Research Req ID: 26740

Shift: Days

Employment Status: AF - Active - Regular - Full Time 

Job Summary

Dr. Kai Wang's research division is seeking  to fill a research technician position in human molecular genetics- the central focus of this role is the use of multiple next-generation sequencing technologies to study genetic mutations associated with human diseases.

More about the Dr. Wang's research is summarized below:

The research Kai Wang, Ph.D. focuses on is the development of bioinformatics methods to improve our understanding of the genetic basis of human diseases, and the integration of electronic health records and genomic information to facilitate genomic medicine on scale. Current projects include the development of computational tools to call structural variants and DNA modifications from long-read sequencing data, the identification/prioritization of disease-relevant genetic mutations, the use of deep neural network to predict prognosis and optimize therapy for patients with cancer, the application of systems biology approaches on single-cell gene expression data, and the data mining on electronic health records to predict genetic syndromes and causal genes.


Preferred applicant:

A suitable candidate should have prior experience in genetics/genomics-related fields, such as molecular biology (DNA/RNA extraction, QC, qPCR, etc), molecular cloning, library preparation for sequencing, informatics software skills such as sequence analysis and primer design, and verbal/written skills to summarize results and presentations. Prior experience with genome editing and cell culture is strongly preferred. This position offers an excellent opportunity to learn and apply skills in human genomics and genetics, and can be authors in high-quality publications. Salary and position level are commensurate with candidate's prior experience and qualification.

Job Responsibilities
  • Independently performs advanced, complex research procedures on experimental samples
  • Formulates and performs complex lab experiments and analyzes reports the data including interpretation of methodologies
  • Performs advanced calculations and maintains appropriate log and lab notebooks
  • Plans and modifies research protocols and procedures with minimal direction from the principal investigator or supervisor
  • Assists in development & troubleshooting of new techniques and ideas
  • Prepares laboratory reagents, monitors and maintains laboratory inventory
  • Supervises, trains and mentors junior and new staff members
  • Determines work assignments, schedules and laboratory priorities
  • Presents & discusses work at weekly lab meetings and national symposia
  • Assists in writing of grants, journal articles, poster and oral presentations
Required Licenses, Certifications, Registrations
Required Education and Experience

Required Education: Bachelor’s Degree


Required Experience: Two (2) years of laboratory experience

Preferred Education, Experience & Cert/Lic

Preferred Education: Bachelor’s Degree


Preferred Experience:

  • Three (3) years of laboratory experience
  • Previous supervisory experience.
Additional Technical Requirements

All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products or nicotine in any form and a negative nicotine screen (the latter occurs after a job offer).

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

VEVRAA Federal Contractor/Seeking priority referrals for protected veterans.  Please contact our hiring official with any referrals or questions.

CHOP Careers Contact 

Talent Acquisition

2716 South Street, 6th Floor

Philadelphia, PA 19146 

Phone: 866-820-9288




Nearest Major Market: Philadelphia

Job Segment: Medical, Patient Care, Informatics, Data Mining, Healthcare, Research, Technology