Research Tech III - Pulmonary Zepp Lab

Philadelphia, PA, US, 19104

​Location: LOC_ABRAMSON-Abramson Building 

Req ID: 221932

Shift: Days

Employment Status: Regular - Full Time 

​About Us
We’re seeking breakthrough makers! Children’s Hospital of Philadelphia was built on the belief that we can change lives. Today, in every role throughout our hospital, research institute and care network, the 22,000 members of our workforce are finding new ways – big and small – to make a difference for the patients and families we serve. 

If you are ready to challenge yourself, be inspired and grow – no matter what your role – you just may be the kind of breakthrough maker who will thrive at CHOP.

​CHOP is proud to share that we are ranked No. 1 on Forbes' 2022 list of America's Best Large Employers!

Job Summary

Job Summary

As part of the Division of Pulmonary and Sleep Medicine, the Lung Research Group at CHOP is dedicated to understanding the cellular and molecular mechanisms underlying lung diseases in children and adults. Ongoing studies in the Zepp laboratory aim to understand how the lung responds to environmental injury and how to repair damaged lung tissue. The Zepp lab is translating these findings to identify molecular targets in lung diseases. The Zepp lab takes a comprehensive approach that includes genetic mouse models, three-dimensional in vitro cell culture, live imaging, and molecular and transcriptomic profiling to interrogate novel cellular processes. We are looking for a new team member to become a central part of our work. The top qualities we’re looking for are a strong work ethic, a good team player, and enthusiasm to make fundamental scientific discoveries. We are a new laboratory with several highly skilled and passionate scientists that will work closely to coach and develop our new team members

The Research Technician will assist and play a central role in lab operations and protocols. About 50% of this position will involve the maintenance and genotyping of our mouse colony. This involves mouse handling, ear notching, DNA extraction, PCR, and good record keeping. The technician will also be responsible for maintaining an up-to-date online electronic database of the mouse colony. Additional work would include helping with general lab upkeep and data collection, analysis, and processing of lung tissue for histology and fluorescent imaging. Additional opportunities to design experiments, analyze data, or develop a project are available if training and time allows.

The ideal candidate will have a BS in Biology or related fields. Previous experience in mouse handling is preferred, and experience in standard laboratory techniques (pipetting, PCR, gel electrophoresis) is strongly preferred. The ideal candidate will be well organized with great attention to detail and the ability to maintain precise notes of all experimental information in a hard-copy and digital format. The initial training period will be used to assess and develop a solid technical foundation. After this time, the ideal technician is expected to be able to work independently to effectively troubleshoot and communicate technical difficulties and work well with others in our Lung Research Group. Occasional work on weekends/evenings may be required. All lab members are expected to maintain a respectful and collegial academic environment.

Job Responsibilities

  • Performs research procedures on experimental samples with minimal supervision
  • Formulates and performs complex lab experiments and analyzes & reports the data
  • Performs tasks that require knowledge of advanced techniques and equipment
  • Performs advanced calculations and maintains appropriate log and lab notebooks
  • Assists with planning specific research protocols and procedures
  • Assists in development & troubleshooting of new techniques and ideas
  • May be required to modify scientific methods and protocols (in conjunction with PI)
  • Checks others results for completeness and accuracy
  • May be responsible for training and mentoring new staff
  • Assists in the preparing of grants journal articles, poster and oral presentations
  • May perform routine and non-routine tests / experiments as needed

Required Education and Experience

Required Education: Associates Degree 

Required Experience: One (1) year of laboratory experience

Preferred Education, Experience & Cert/Lic

Preferred Education: Bachelor’s Degree

Preferred Experience: Previous experience in mouse handling is preferred, and experience in standard laboratory techniques (pipetting, PCR, gel electrophoresis) is strongly preferred.


Additional Technical Requirements

To carry out its mission, it is of critical importance for the Children’s Hospital of Philadelphia (CHOP) to keep our patients, families and workforce safe and healthy and to support the health of our global community. In keeping with this, CHOP has mandated all workforce members on site at any CHOP location for any portion of their time be vaccinated for COVID-19 as a condition of employment.  This mandate also applies to workforce members performing work for CHOP at non-CHOP locations. Additionally, all workforce members based in or regularly scheduled to work at any New Jersey location are mandated to be both vaccinated and boosted for COVID-19, with booster timing consistent with applicable guidelines. The CHOP COVID-19 vaccine mandate is in alignment with applicable local, state and federal mandates. CHOP also requires all workforce members who work in patient care buildings or who provide patient care to receive an annual influenza vaccine. Employees may request exemption consideration for CHOP vaccine requirements for valid religious and medical reasons.  Please note start dates may be delayed until candidates are fully immunized or valid exemption requests are reviewed. In addition, candidates other than those in positions with regularly scheduled hours in New Jersey, must attest to not using tobacco products.
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