Research Tech III - Human Genetics

Philadelphia, PA, US, 19104

Job Type: 

LOC_ABRAMSON-Abramson Building Req ID: 75761

Shift: Days

Employment Status: Regular - Full Time 

Job Summary

Research technical position in a new translational research laboratory focused on developing therapies for pediatric neurogenetic disorders. The primary focus of the lab is to improve our understanding of how genetic disorders that disrupt brain metabolism alter the electrical activity of the brain and lead to the clinical symptoms that these children experience. The lab uses a variety of techniques including physiological, molecular, and genetic, to reach our goal. With these techniques, we aim to develop drugs that not only correct the metabolic defect but also improve the function of electrical circuits in the brain to treat symptoms such as seizures and intellectual disability. 

We are looking for a person who is bright, intellectually curious, and motivated to both learn new techniques and/or apply any skills they may have already developed to our work. A willingness to perform studies on animal models of disease (mouse models) is required.

Responsibilities will include:

•Performing experiments utilizing mouse models of disease, initially directly under the supervision of others but overtime independently.  Techniques will include histology, cell culture, animal surgeries, and behavioral assays.
•Maintenance of mouse colony, including management of breeding and genotyping
•Helping with lab organization
•Supervision and orientation of new and rotating lab members

Job Responsibilities
  • Performs research procedures on experimental samples with minimal supervision
  • Formulates and performs complex lab experiments and analyzes & reports the data
  • Performs tasks that require knowledge of advanced techniques and equipment
  • Performs advanced calculations and maintains appropriate log and lab notebooks
  • Assists with planning specific research protocols and procedures
  • Assists in development & troubleshooting of new techniques and ideas
  • May be required to modify scientific methods and protocols (in conjunction with PI)
  • Checks others results for completeness and accuracy
  • May be responsible for training and mentoring new staff
  • Assists in the preparing of grants journal articles, poster and oral presentations
  • May perform routine and non-routine tests / experiments as needed
Required Education and Experience

Required Education: Associates Degree or active enrollment in a Bachelor’s Degree Program


Required Experience: One (1) year of laboratory experience

Preferred Education, Experience & Cert/Lic

Preferred Education: Bachelor’s Degree


Preferred Experience: Two (2) years of laboratory experience


All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products or nicotine in any form and a negative nicotine screen (the latter occurs after a job offer).

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

VEVRAA Federal Contractor/Seeking priority referrals for protected veterans.  Please contact our hiring official with any referrals or questions.

CHOP Careers Contact 

Talent Acquisition

2716 South Street, 6th Floor

Philadelphia, PA 19146 

Phone: 866-820-9288