Research Assoc I - CAR T Cell-based Cancer Immunotherapies- Maris Lab

Philadelphia, PA, US, 19104

Location: LOC_COLKET-Colket Translational Research 

Req ID: 148794

Shift: Days

Employment Status: Regular - Full Time 

Job Summary

We are seeking a highly motivated Research Associate to perform various functions within a growing team focused on the development of immunotherapies for pediatric cancers with high unmet needs. RA will join a dynamic multidisciplinary group focused on developing novel CAR T cells involving all stages of the immunotherapy development pipeline: target discovery, CAR engineering, optimization, preclinical testing, and clinical development.

The RA will be responsible for performing independent experiments, developing and optimizing assays, and collecting/analyzing/interpreting/presenting data. RA will be exposed to a broad range of experimental approaches covering the entire developmental process of new immunotherapies. This work will build on a publication currently in press at Nature as well as focus on developing the next generation of cellular therapies.

The RA will work as part of local and international multidisciplinary teams funded by Stand Up To Cancer and the Biden Cancer Moonshot initiatives, and will benefit from exposure to local and off-site expertise, collaborations, and scientific meetings.

Prior experience in immunological, biochemical and molecular biology techniques preferred. Techniques include, but are not limited to: PCR, flow cytometry, cell culture, cloning, vector production, immunological assays, protein engineering, mass spectrometry, and single-cell sequencing.

RA will participate in development of therapies intended for clinical translation. Individuals will have the opportunity to develop independent projects and execute them under direct supervision.

Preferred Education and Experience:

PhD and/or industry experience preferred. Preference given to applicants with prior experience in any of the following: proteomics, molecular biology and immunology assays. Computational experience preferred but not required. This work will build on the recent publication:  https://www.nature.com/articles/s41586-021-04061-6

Job Responsibilities

  • Assists faculty in the conduct of research of significant value in the basic and/or translational science area
  • Plans, conducts research projects within the federal, institutional regulations and policies
  • Collaborates with researchers, external agencies and institutions to develop cooperative research initiatives
  • Trains technical staff, students in lab procedures
  • Reviews manuscripts for peer-reviewed journals
  • Assists with the submission of grant applications, contracts and research projects funding
  • Participates in free discussion, research progress, and overall morale
  • Responsible for appropriate use of research funds
  • May supervise students

Required Licenses, Certifications, Registrations


Required Education and Experience

Required Education: Bachelor’s degree

Required Experience: One (1) year of scientifically relevant experience

Preferred Education, Experience & Cert/Lic

Preferred Experience: 

  • Terminal degree (MD, PhD, DVM) with one (1) year Post-Doctoral fellowship experience OR
  • Master’s degree, three (3) or more years of scientifically relevant experience OR
  • Bachelor’s degree, seven (7) or more years of scientifically relevant experience

Additional Technical Requirements

All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products.

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

VEVRAA Federal Contractor/Seeking priority referrals for protected veterans.  Please contact our hiring official with any referrals or questions.

CHOP Careers Contact 

Talent Acquisition

2716 South Street, 6th Floor

Philadelphia, PA 19146 




Nearest Major Market: Philadelphia

Job Segment: Immunology, Medical, Oncology, Cancer Research, Healthcare, Research