Research Assoc I-Grohar lab

Philadelphia, PA, US, 19104

Job Type: 

COLKET - Colket Translational Research Req ID: 26966

Shift: Days

Employment Status: AF - Active - Regular - Full Time 

Job Summary

The Grohar Lab is seeking a person interested in the position of Research Associate.

The Grohar lab is focused on developing new targeted therapies to treat pediatric solid tumors.  We work on challenging drug targets, such as transcription factors, that are considered by many to be “undruggable.” The lab has primarily focused on Ewing sarcoma and the development of therapies that target the EWS-FLI1 transcription factor. More recently, we have extended our focus to other solid tumors with the goal of better understanding therapeutic vulnerabilities at the interface of transcription and epigenetics. We have a number of compounds in various stages of clinical development including a clinical trial based on our laboratory work that is set to open in the coming months. We employ high-throughput genetic and chemical screens to identify novel targets and compounds, molecular pharmacology to understand the mechanism of action, and a variety of next-generations sequencing assays to delineate the effects genome-wide.

We seek an applicant with a passion for therapeutic development for pediatric cancer with excellent interpersonal and leadership skills. The candidate should be interested in working in an enthusiastic environment that is team-oriented. The ideal applicant should have a MS, PhD, or equivalent experience. The position would entail working directly with Dr. Grohar to oversee daily laboratory operations, driving primary research projects as well as training students and fellows. The applicant should also have an interest in growing the interface between the laboratory and the clinic. Animal experience is preferred but not required.


Job Responsibilities
  • Assists faculty in the conduct of research of significant value in the basic and/or translational science area
  • Plans, conducts research projects within the federal and institutional regulations and policies
  • Collaborates with researchers, external agencies and institutions to develop cooperative research initiatives
  • Trains technical staff, students in lab procedures
  • Reviews manuscripts for peer-reviewed journals
  • Assists with the submission of grant applications/contracts and funding of research projects
  • Participates in free discussion, research progress, and overall morale
  • Responsible for appropriate use of research funds
  • May supervise students
Required Licenses, Certifications, Registrations
Required Education and Experience
  • Terminal degree (MD, PhD, DVM),  1or more years Post-Doctoral fellowship experience
  • Master’s degree, 3-5 years of scientifically relevant experience required
  • Bachelor’s degree, 7+ years of scientifically relevant experience required
Preferred Education, Experience & Cert/Lic
Additional Technical Requirements

All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products or nicotine in any form and a negative nicotine screen (the latter occurs after a job offer).

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

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Phone: 866-820-9288




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