Res Post Doc Fellow-Research lab of Dr. Amanda Ackermann

Philadelphia, PA, US, 19104

Job Type: 

Req ID: 26043

Shift: Days

Employment Status: AF - Active - Regular - Full Time 

Job Summary

A postdoctoral fellow (postdoc) position is open in the translational research lab of Dr. Amanda Ackermann (  Our group studies beta cell dysfunction in diabetes and congenital hyperinsulinism, with the goal of identifying novel therapeutic targets.  We use a variety of approaches, including genetic and epigenetic manipulation, genomic analyses, and physiological testing of primary human tissue, mouse models, and cell lines.

The postdoctoral fellow (postdoc), under the direction/guidance of Dr. Ackermann, will help lead a new specific research project to create and characterize a mouse model of Hyperinsulinism/Hyperammonemia (HI/HA) Syndrome, which has multi-organ phenotypes including of the beta cell, central nervous system, kidney, and liver.  This project will require DNA cloning, CRISPR, in vivo mouse metabolic and neurologic phenotyping, and histologic analysis.  The postdoc must have a terminal degree (PhD) in a relevant field and at least one first-author manuscript published or submitted.  Prior experience performing mouse studies is desired.



Job Responsibilities (Continued)

The postdoc experience will serve to extend, refine and enhance skills necessary for professional and career development, and will enable the individual to broaden his/her scientific background by acquiring new research capabilities.  It is expected that this individual will conduct independent scholarly research, and will contribute directly to the overall research goals of the project and the research group.  Postdocs will be expected to participate in project planning, recording and interpretation/evaluation of data, and communication of results.  Postdocs will also be expected to acquire technical, lab management, and manuscript/grant writing skills; and participate in seminars, lectures, poster sessions and presentations at national meetings.  Postdoctoral fellows also may be required to supervise junior lab members, develop new methods and protocols for research, and assist with the development of other research projects in the lab.


Postdoctoral fellows at CHOP receive mentored translational science training in a rich scientific environment that includes both CHOP and University of Pennsylvania research communities, with state-of-the-art research core facilities and multiple career-development programs for trainees.  Competitive salaries are provided along with excellent fringe benefits.  The Ackermann Lab is located within a larger beta cell research group at the Abramson Pediatric Research Center.  We collaborate with multiple lab groups at CHOP and Penn and actively participate in several centers and institutes across the institutions.



PhD in relevant field, such as biology, physiology, genetics

First-author manuscript published or submitted

Strong research skills

Effective problem solving/critical thinking skills

Ability to work independently and with a strong work ethic

High level of motivation

Excellent communication/interpersonal skills

Job Responsibilities
  1. Conduct independent scholarly research and develop new methods and protocols
  2. Participate in project planning, recording and evaluation of data
  3. Acquire technical, lab management and grant writing skills
  4. Participate in seminars, lectures, poster sessions and presentation at national meetings
  5. Supervise junior lab members
  6. Assist with other research projects
Required Licenses, Certifications, Registrations
Required Education and Experience
  • A terminal degree PhD, MD, DVM, etc.
  • According to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing
Preferred Education, Experience & Cert/Lic
Additional Technical Requirements

All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products or nicotine in any form and a negative nicotine screen (the latter occurs after a job offer).

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

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