Res Post Doc Fellow - Pediatric Brain Tumor Research

Philadelphia, PA, US, 19104

Location: LOC_COLKET-Colket Translational Research 

Req ID: 147254

Shift: Any

Employment Status: Regular - Full Time 

Job Summary

A Research Post Doc Fellow position is available in the laboratory of Dr. Jessica Foster at the Center for Childhood Cancer Research at the Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania (UPENN). This position is part of a research program to develop immunotherapies for pediatric brain tumors. The laboratory uses mouse models as well as cell lines and patient-derived xenografts to recapitulate the human disease and test novel therapeutics. Our main focus is developing chimeric antigen receptor (CAR) T cell approaches for pediatric brain tumors. This highly translational work will be used to inform clinical trials for pediatric patients.

Strong experimental skill in basic molecular biology techniques are a prerequisite (DNA, RNA, protein analysis, cloning, cell culture, multi-parameter flow cytometry, cytotoxicity).

Strong preference will be given to candidates with at least two or more of the following specific skills:

  • Experience in mouse brain tumor models, including stereotactic surgery
  • Experience in genetically engineered models of cancer, including breeding, neonatal surgery, and colony maintenance
  • Experience in advanced confocal microscopy
  • Experience in advanced in vivo imaging techniques including IVIS and MRI
  • Experience in adoptive cellular therapeutics



Job Responsibilities (Continued)

The successful candidate will:

  • Plan, conduct, and manage research projects within the federal and institutional regulations and policies
  • Assist the PI in the conduct of research of significant value in the basic and/or translational science area
  • Collaborate with researchers, external agencies and institutions to develop cooperative research initiatives around immunotherapy for pediatric brain tumors
  • Order research supplies, responsible for appropriate use of research funds
  • Train technical staff, students, fellows & physicians in lab procedures. May supervise some staff and students
  • Review manuscripts for peer-reviewed journals
  • Assist in composing/developing applications for grants/contracts for funding of research projects
  • Promote free discussion, research progress, and overall morale

Job Responsibilities (Continued)

Required Licenses, Certifications, Registrations

Required Education and Experience

  • A terminal degree PhD, MD, DVM, etc.
  • According to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing

Preferred Education, Experience & Cert/Lic

Additional Technical Requirements

All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products.

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

VEVRAA Federal Contractor/Seeking priority referrals for protected veterans.  Please contact our hiring official with any referrals or questions.

CHOP Careers Contact 

Talent Acquisition

2716 South Street, 6th Floor

Philadelphia, PA 19146 




Nearest Major Market: Philadelphia

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