Res Post Doc Fellow - Genetic Regulation of the Skeleton in Health and Disease

Philadelphia, PA, US, 19104

Job Type: 

Req ID: 22881

Shift: Days

Employment Status: AF - Active - Regular - Full Time 

Job Summary


Postdoctoral Positions in Genetic Regulation of the Skeleton in Health and Disease

Postdoctoral fellow positions will be available starting in July of 2018 in the newly relocated research laboratory of Dr. Véronique Lefebvre in the Division of Orthopaedic Surgery at the Children’s Hospital of Philadelphia (CHOP).

The fellows will drive projects on molecular mechanisms specifying skeletal stem cell identity and self-renewal and driving chondrocyte and osteoblast differentiation and activity. Several projects will assess the roles and regulation of SOX transcription factors in these processes. Other projects will uncover molecular pathways underlying specific forms of human skeletal diseases, including chondrodysplasias, osteoarthritis and osteoporosis. The fellows will use cutting-edge approaches in vivo and in vitro, including mouse genetic models and next-generation sequencing. New findings are anticipated to generate a better understanding of human diseases, and to help develop novel therapeutic approaches for these diseases. Successful accomplishment of the projects will allow the fellows to launch promising research careers in stem cell and molecular genetics relevant to both rare and prevalent human skeletal diseases.  

Candidates must have a recent Ph.D. degree in biological sciences and a solid publication record in top-tier scientific journals. Previous expertise and eagerness to learn in the following areas is desired: skeletal biology, stem cell biology, mouse models, and high-throughput sequencing approaches. Candidates should demonstrate proficiency in written and spoken English and in communicating scientific research findings accurately and efficiently. First-rate interpersonal and organizational skills are also recommended.

The CHOP Research Institute offers an exceptionally interactive and front-line scientific environment with state-of-the-art research core facilities and with multiple career-development programs for trainees. It recognizes the power of a diverse community and encourages applications from individuals with varied experiences, perspectives, and backgrounds. Competitive salaries are provided along with excellent fringe benefits. 

Interested candidates should send a CV, a description of research interests and career goals, and contact information for three references to Dr. Veronique Lefebvre (LEFEBVREV1@EMAIL.CHOP.EDU).

Job Responsibilities

  1. Conduct independent scholarly research and develop new methods and protocols
  2. Participate in project planning, recording and evaluation of data
  3. Acquire technical, lab management and grant writing skills
  4. Participate in seminars, lectures, poster sessions and presentation at national meetings
  5. Supervise junior lab members
  6. Assist with other research projects

Required Education and Experience

  • A terminal degree PhD, MD, DVM, etc.
  • According to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing

All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products or nicotine in any form and a negative nicotine screen (the latter occurs after a job offer).

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

VEVRAA Federal Contractor/Seeking priority referrals for protected veterans.  Please contact our hiring official with any referrals or questions.

CHOP Careers Contact 

Talent Acquisition

2716 South Street, 6th Floor

Philadelphia, PA 19146 

Phone: 866-820-9288




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