Res Post Doc Fellow - Biomedical and Health Informatics (DBHI)

Philadelphia, PA, US, 19104

Job Type: 

Req ID: 24081

Shift: Days

Employment Status: AF - Active - Regular - Full Time 

Job Summary

A postdoctoral fellow position is open in the Tan research group in the Department of Pediatrics at the University of Pennsylvania and the Department of Biomedical and Health Informatics (DBHI) at the Children’s Hospital of Philadelphia (CHOP).


The Tan research group ( is interdisciplinary and highly collaborative, utilizing both computational and experimental approaches to study gene regulation. We have pioneered multiple computational algorithms for regulatory genomics, epigenomics, and network biology. Specific projects will be defined by the candidates (and based on the candidates expertise) and with input from Dr. Tan and our close collaborators at the Center for Childhood Cancer Research CHOP and Abramson Cancer Center at the University of Pennsylvania.


The desired candidate must have a terminal degree (PhD) in computational biology, genetics, molecular biology, computer science, statistics, mathematics or related field with a strong understanding of biology. The postdoctoral fellow will be responsible for development of novel computational algorithms and/or experimental approaches to understand gene regulation in normal and cancer development. Specific research areas include:


1. Regulatory genomics. Focusing on generating insights into how mutations in regulatory DNA sequences contribute to development and oncogenesis.

2. Cancer systems biology. Focusing on generating insights into the relationship between the dynamics of gene networks during cancer development.

3. Algorithms for single-cell analysis. Focusing developing statistical methods for analyzing single-cell transcriptome and epigenome data.


CHOP postdoctoral fellows receive mentored training in a rich scientific environment that includes both CHOP and University of Pennsylvania research communities. CHOP is an interdisciplinary institution dedicated to conducting basic, clinical and translational research with a particular focus on conditions that affect children.


Interested candidates please send CV and three reference letters to Kai Tan,

Job Responsibilities

  1. Conduct independent scholarly research and develop new methods and protocols
  2. Participate in project planning, recording and evaluation of data
  3. Acquire technical, lab management and grant writing skills
  4. Participate in seminars, lectures, poster sessions and presentation at national meetings
  5. Supervise junior lab members
  6. Assist with other research projects

Required Education and Experience

  • A terminal degree PhD, MD, DVM, etc.
  • According to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing

All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products or nicotine in any form and a negative nicotine screen (the latter occurs after a job offer).

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

VEVRAA Federal Contractor/Seeking priority referrals for protected veterans.  Please contact our hiring official with any referrals or questions.

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Talent Acquisition

2716 South Street, 6th Floor

Philadelphia, PA 19146 

Phone: 866-820-9288




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