Philadelphia, PA, US, 19104

Job Type: 

Req ID: 25366

Shift: Any

Employment Status: AF - Active - Regular - Full Time 

Job Summary


The mission of the Mitochondrial Medicine Frontier Program (MMFP) at The Children’s Hospital of Philadelphia is to become the premiere center in the world to provide integrated multi-disciplinary care, advanced diagnostics and therapeutics, and individualized basic, translational, and clinical research programs to improve the health of patients of all ages living with mitochondrial disease ( As part of that vision, we seek to recruit a dedicated MD or MD, PhD fellow in ANY CLINICAL FIELD who seeks to advance their knowledge in clinical care and clinical or translational research in mitochondrial disease. We are excited to offer a new 1 year fellowship program, with rolling availability to start at any time in 2019. Salary and benefits are commensurate with experience and training.

This unique fellowship opportunity is located fully within the Children’s Hospital of Philadelphia (CHOP) Mitochondrial Medicine Frontier Program, and may be modified to maximize a successful applicant’s career goals. The fellow will engage in the clinical care of individuals in both outpatient and inpatient settings for suspected or definite mitochondrial disease, with current volumes of nearly 1,000 annual visits from patients in 44 states and 8 countries. They will work with 4 faculty members who provide mitochondrial focused evaluations and management of children and adults with primary mitochondrial disease, while also conducting clinical and/or basic research focused in mitochondrial medicine. The mitochondrial medicine program is supported by an integrated team of three highly-expert genetic counselors, two registered nurses, dedicated administrative support, a mitochondrial dietician, physical therapists, exercise physiology assessment, financial counselor, and social worker. The fellow will also have the opportunity to work with expert mitochondrial disease specialists accessible to patients in 15 different clinical divisions at CHOP and half a dozen more at the Hospital of the University of Pennsylvania, physicians who are highly knowledgeable about and committed to improving integrated clinical care for mitochondrial disease patients ( Through this work, the fellow will gain expertise in cutting-edge diagnostics, new clinical test development and interpretation, patient counseling, and expert care management guidelines.

During their clinical time in this training year, the fellow is mainly responsible for regular participation in the care of mitochondrial medicine patients seen in the CHOP Mitochondrial Medicine Frontier Program outpatient clinics and coverage of the inpatient mitochondrial medicine consult service. The fellow is supervised at all times by an attending physician. Every patient seen by the fellow is discussed with an attending physician in clinic or on the consult service, and presented for discussion in weekly mitochondrial medicine multi-disciplinary clinical care and pathology case results conferences that the fellow will coordinate. By the end of the year, the fellow will be competent in performing diagnostic evaluations of mitochondrial disease including genetic and biochemical test interpretation, as well as performing and interpreting results of skin and percutaneous needle muscle biopsies. The fellow will be expected to give lectures on mitochondrial medicine to residents and student trainees. Weekend consult coverage will be expected for two weeks and two weekends per month.



Job Responsibilities


Interested fellows will also have the opportunity to regularly participate in clinical research to better characterize the natural history and organ-specific areas affected by mitochondrial disease, as well as multiple pharma-sponsored clinical trials underway in both children and adults with primary mitochondrial disease. They will be given the opportunity to participate in a year-long R25 Rare Disease clinical research course offered at the National Institutes of Health, as well as in monthly mitochondrial medicine fellows conferences sponsored by the North American Mitochondrial Disease Consortium.

Candidates interested in translational research will have the opportunity to adjust their clinical time to arrange to work with a collaborative team of CHOP research scientists who work to functionally validate novel mitochondrial disease genes, investigate the mechanistic subtleties of different types of mitochondrial disease, and develop precision therapies tailored to each mitochondrial disease subtype and clinical disorder. A suite of robust pre-clinical cellular and animal model systems are available in which to decipher precise disease mechanisms and effectively screen, validate,optimize, and de-risk therapies for diverse mitochondrial disease in academic-pharma partnerships as well as develop novel diagnostic methods for mitochondrial disease.

This fellowship is a non-ACGME accredited position and completion does not lead to board certification. Individuals with permanent US status and an MD degree at any level of training who are eligible for an independent MD/DO license (but not training license) are eligible to apply. Residency or fellowship training in any field or specialty (pediatric or adult) is acceptable. Applicants will be prioritized who seek to establish their career involving any aspect of Mitochondrial Medicine. Minorities and individuals of any gender are encouraged to apply. It is anticipated one fellow will be selected in each of the next 3 years (2019, 2020, 2021) – inquiries about off-cycle starts and future year planning are welcome.


Interested applicants should prepare and submit the following information:

1. Personal Statement detailing background and interest in the CHOP Mitochondrial Medicine Fellowship. Include availability and preferred start dates for program participation.

2. Completed application

3. Updated CV

4. Three letters of recommendation

5. Dean’s Letter (MSPE)

6. Medical School Transcript

7. USMLE parts 1, 2 and 3, taken within the 7-year time frame as required by the Commonwealth of Pennsylvania, or equivalent scores

8. If a graduate of a medical school outside the United States, Canada or Puerto Rico, valid ECFMG certificate or one that does not expire prior to the start of the fellowship

Completed applications should be sent by email or mail to:

Marni J. Falk, MD

Executive Director, Mitochondrial Medicine Frontier Program

Children’s Hospital of Philadelphia

ARC 1002c, 3615 Civic Center Blvd, Philadelphia, PA 19104

Phone: 215-590-4564

Email: falkm@

Required Licenses and Experience

PA License
DEA Certificate Number
NJ License (If practicing in New Jersey) 
CDS (New Jersey drug enforcement)
Foreign Medical Students must be certified by ECFMG

All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products or nicotine in any form and a negative nicotine screen (the latter occurs after a job offer).

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

VEVRAA Federal Contractor/Seeking priority referrals for protected veterans.  Please contact our hiring official with any referrals or questions.

CHOP Careers Contact 

Talent Acquisition

2716 South Street, 6th Floor

Philadelphia, PA 19146 

Phone: 866-820-9288




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