Laboratory Research Technician II (Leukodystrophy Center)

Philadelphia, PA, US, 19104

Job Type: 

Req ID: 25923

Shift: Days

Employment Status: AF - Active - Regular - Full Time 

Job Summary

The Research Technician II will support the basic science components of the Myelin Disorders Biorepository Project (MDBP), an international patient registry that seeks to collect and analyze clinical data and biological samples from patients with suspected or confirmed leukodystrophies, a group of approximately 31 rare genetic disorders that affect development of the white matter of the brain, predominantly in pediatric populations. MDBP researchers are currently focused on uncovering novel genetic etiologies within this group of disorders, identifying key biomarkers, and developing a repository of natural history data to support clinical trial development.



The Research Technician II will work closely with senior scientific staff to support key functions of the biorepository and other grant-specific projects. Routine responsibilities may mouse colony support (inc. breeding, identification, genotyping), human tissue sample processing (inc. nucleic acid extraction, PBMC purification), cell culture work, and maintenance of the REDCap-based biorepository database. Once proficiency has been attained for these basic tasks, the Research Technician II will have an opportunity to be trained in more advanced scientific techniques.



The biorepository is a high-volume, fast-paced project, and a successful candidate must be able to demonstrate an ability to multi-task. Prior experience working or volunteering in a basic science laboratory is strongly preferred. Outstanding written and oral communication skills are essential, as the position involves regular contact with physicians and clinical staff in the CHOP Leukodystrophy Center, and occasionally with patients and their families.



This position is intended for individuals interested in a career in in the basic or health sciences, and a successful applicant must have a demonstrable passion for academic research, as well as a desire to make meaningful contributions to a growing body of knowledge. The Vanderver Lab is a founding member of the Global Leukodystrophy Initiative (GLIA), an international consortium of clinicians, researchers, and disease advocates that seeks to build collaborative partnerships and will serve as a platform for industry-sponsored clinical trials.

Job Responsibilities

  • Performs routine tests under the direction of principal investigator or supervisor
  • Performs research procedures on experimental samples as directed
  • Records and checks results for completeness and accuracy
  • Performs calculations and maintains appropriate log and lab notebooks
  • Performs tasks that require familiarity with fundamental techniques and equipment
  • Assists with planning specific research protocols and procedures
  • Maintains office, lab area, reagents, supplies and equipment
  • Cleans and performs routine maintenance on lab equipment
  • Coordinates schedules of tests & procedures
  • Attends courses, seminars, and lab meetings to expand knowledge of research and laboratory techniques
  • Records results, organizes data and maintains lab notebook in an organized manner
  • Conducts literary searches as directed

Required Education and Experience

Required Education: Associates Degree or active enrollment in a Bachelor’s Degree Program


Required Experience: Nine (9) months of laboratory experience

Preferred Education, Experience & Cert/Lic

Preferred Education: Bachelor’s Degree


Preferred Experience:

  • Eighteen (18) months of laboratory experience
  • Related internship experience.



All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products or nicotine in any form and a negative nicotine screen (the latter occurs after a job offer).

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

VEVRAA Federal Contractor/Seeking priority referrals for protected veterans.  Please contact our hiring official with any referrals or questions.

CHOP Careers Contact 

Talent Acquisition

2716 South Street, 6th Floor

Philadelphia, PA 19146 

Phone: 866-820-9288




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