Core Facility Technical Director - NG Sequencing

Philadelphia, PA, US, 19104

Job Type: 

LOC_COLKET-Colket Translational Research Req ID: 72062

Shift: Days

Employment Status: Regular - Full Time 

Job Summary

The Children’s Hospital of Philadelphia (CHOP) is seeking a highly qualified and innovative technical director to lead a high-throughput sequencing core facility. This high-throughput sequencing core will develop and implement standardized and specialized library preparation protocols, provide sequencing services, and advise laboratory personnel in experimental design and analysis. The long-term goal of this core facility will be to provide a wide range of genomics services for CHOP research faculty. Staffing of the core, and instrumentation needed to keep pace with anticipated demand and emerging technologies, will be provided by the CHOP Research Institute. Once this state-of-the-art facility is established, the technical director will be expected to develop a sustainable strategic plan, and work with faculty to prioritize future instrumentation and services. The technical director is expected to interact and interface with various genomics-focused research centers and programs, and contribute to the overall ecosystem of genomics and data sciences research at CHOP. The successful applicant will be a visionary leader with significant experience in contemporary high-throughput sequencing technologies and instruments, and in managing research personnel and technical staff. A candidate with prior experience in directing and managing a sequencing core facility is preferred.


Takes primary responsibility with the Faculty-Director for leading the Core’s mission and strategic vision and overseeing all designated Core Facility activities.  In particular, the incumbent will:

  • Identify and manage strategic vision for the core including research agenda, core lab personnel needs, budget planning and management;
  • Manage core budget and finances; and
  • Manage core personnel;


Work closely with the Chair of the Institutional Core Advisory Committee (iCAC) to manage short term and long term goals for the technical direction of the core laboratory. Work with the iCAC Chair and Director of Research Core Services to ensure that the Core Lab is providing optimal service and outstanding customer service. The Director must be accessible to the laboratory all the time by various means.


The Research Core Facility Technical Director is responsible for overall supervision of the Core Laboratory and manages the research staff and core laboratory operations. Develops new experimental procedures and core lab services as needed. Collaborates and interacts with other researchers within the institution and at other institutions.  Prepares laboratory progress reports, and laboratory budget plans. Serves as resource person for research colleagues and a mentor for less experienced research personnel. Works directly with the Director for Core Services to price service offerings in accordance with federal guidelines. 

Job Responsibilities

1. Responsible for all technical work performed.

  • Develop, test, implement and evaluate new and creative approaches to meeting core lab and institutional goals.
  • Initiate and appropriately respond to initiatives from others to establish and evaluate integrated systems to improve services that are supportive of the mission of the Hospital and Research Institute
  • Collaborates with researchers, external agencies and institutions to develop cooperative research initiatives
  • Responsible for the development, implementation and evaluation of services, programs, protocols, policies and procedures, and performance standards
  • Participate in the collection and reviewing of data from Hospital-wide and specific departmental customer survey programs.
  • Ensure that all the necessary remedial actions are taken and documented whenever significant deviation from laboratory’s established performance characteristics is identified and that test/sample/project results are reported only when the system is functioning properly.
  • Ensure that consultation is available to the laboratory clients on matters relating to the quality and interpretation of the test results reported.


2. Directs all technical and non-technical personnel.

  • Create and support an environment to foster teamwork, cooperation, respect and diversity.
  • As a leader and role model, participate in professional and community activities on a routine basis.
  • Provide direction regarding overall laboratory staffing and specific research projects
  • Direct personnel efforts in achieving the strategic plan for the laboratory
  • Monitor absenteeism and tardiness noting effects on other personnel and section operations.
  • Responsible for hiring, counseling and termination of staff according to CHOP policies.
  • Track annual performance reviews of staff.


3. For Clinical Laboratories, assures that licensing and accreditation requirement are in full compliance.

  • Participate and passes all proficiency testing.
  • Stays within federal and state guidelines.
  • Ensures all procedure manuals are up-to-date.
  • Reviews procedure manuals annually.
  • Oversees compliance with all accreditation and regulatory agencies governing the standards for clinical laboratory services.
Required Education and Experience

M.D. or Ph.D. degree in laboratory medicine and five years or greater experience in the field. (MA / MS degree with 5 years of supervisory experience in the field may be substituted for terminal degree)

Additional Technical Requirements
  • Proficiency in the use of a wide variety of lab techniques, research equipment and research related software.
  • Proficiency with Information Systems used within the department.
  • Ability to handle confidential materials.
  • Ability to work the “bench” when necessary.
  • Communication, technical, and organizational skills.
  • Ability to handle and interpret data.                                                                                                                                                               

All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products.

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

VEVRAA Federal Contractor/Seeking priority referrals for protected veterans.  Please contact our hiring official with any referrals or questions.

CHOP Careers Contact 

Talent Acquisition

2716 South Street, 6th Floor

Philadelphia, PA 19146 




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